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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1999-7-27
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pubmed:abstractText |
It is commonly assumed that renal function, and in parallel the excretion of drugs, is considerably reduced in the elderly. Endogenous creatinine clearance or indirect estimates of this parameter are generally recommended for adapting drug dosage. The present study evaluates the validity of both assumptions.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0031-6970
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
205-11
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:10379636-Adrenergic beta-Antagonists,
pubmed-meshheading:10379636-Adult,
pubmed-meshheading:10379636-Aged,
pubmed-meshheading:10379636-Aging,
pubmed-meshheading:10379636-Atenolol,
pubmed-meshheading:10379636-Creatinine,
pubmed-meshheading:10379636-Diuretics,
pubmed-meshheading:10379636-Female,
pubmed-meshheading:10379636-Glomerular Filtration Rate,
pubmed-meshheading:10379636-Hemodynamics,
pubmed-meshheading:10379636-Humans,
pubmed-meshheading:10379636-Hydrochlorothiazide,
pubmed-meshheading:10379636-Kidney,
pubmed-meshheading:10379636-Kidney Function Tests,
pubmed-meshheading:10379636-Male,
pubmed-meshheading:10379636-Nootropic Agents,
pubmed-meshheading:10379636-Pharmacokinetics,
pubmed-meshheading:10379636-Piracetam,
pubmed-meshheading:10379636-Triamterene
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pubmed:year |
1999
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pubmed:articleTitle |
Renal handling of drugs in the healthy elderly. Creatinine clearance underestimates renal function and pharmacokinetics remain virtually unchanged.
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pubmed:affiliation |
Department of Internal Medicine, Ruperto-Carola University, Heidelberg, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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