rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
1999-8-2
|
pubmed:abstractText |
Nitric oxide (NO) is involved in inflammation and host defence of the lung. It has been found in increased concentrations in the airways in asthmatic subjects but its levels in patients with chronic obstructive pulmonary disease (COPD) have not been investigated. A study was undertaken to determine whether markers of NO metabolism (NO in exhaled air, iNOS expression in sputum cells, and nitrite + nitrate (NO2-/NO3-) in sputum supernatant) are increased in subjects with COPD, and whether they correlate with inflammatory indices in induced sputum. The associations of these markers with smoking were also assessed.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-10377197,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-746496,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-7504773,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-7507065,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-7508323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-7535247,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-7543345,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-7551380,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-7768008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-7952595,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-8499054,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-8564092,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-8630613,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-8880102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-8884218,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-8977600,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-8993004,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-9155829,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-9517624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10377200-9817151
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
pubmed:issn |
0040-6376
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
54
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
576-80
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pubmed:dateRevised |
2011-10-27
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pubmed:meshHeading |
pubmed-meshheading:10377200-Aged,
pubmed-meshheading:10377200-Biological Markers,
pubmed-meshheading:10377200-Breath Tests,
pubmed-meshheading:10377200-Case-Control Studies,
pubmed-meshheading:10377200-Female,
pubmed-meshheading:10377200-Forced Expiratory Volume,
pubmed-meshheading:10377200-Humans,
pubmed-meshheading:10377200-Leukocyte Count,
pubmed-meshheading:10377200-Lung,
pubmed-meshheading:10377200-Lung Diseases, Obstructive,
pubmed-meshheading:10377200-Male,
pubmed-meshheading:10377200-Middle Aged,
pubmed-meshheading:10377200-Nitrates,
pubmed-meshheading:10377200-Nitric Oxide,
pubmed-meshheading:10377200-Nitric Oxide Synthase,
pubmed-meshheading:10377200-Nitric Oxide Synthase Type II,
pubmed-meshheading:10377200-Nitrites,
pubmed-meshheading:10377200-Smoking,
pubmed-meshheading:10377200-Sputum
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pubmed:year |
1999
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pubmed:articleTitle |
Markers of nitric oxide metabolism in sputum and exhaled air are not increased in chronic obstructive pulmonary disease.
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pubmed:affiliation |
Department of Pulmonology, University Hospital, Groningen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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