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| pubmed-article:10375395 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:10375395 | pubmed:dateCreated | 1999-7-15 | lld:pubmed |
| pubmed-article:10375395 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10375395 | pubmed:abstractText | This paper describes the isolation and primary structure analysis of a new phospholipase A2 with platelet-aggregation-inhibiting activity from the venom of Bothrops jararaca. The protein, named BJ-PLA2, was isolated by means of ammonium sulfate precipitation and anion-exchange and reversed-phase chromatographies and behaved as a homogeneous single-chain protein on SDS-PAGE. Its amino acid sequence was determined by N-terminal sequencing and analysis of overlapped chemical and proteolytic fragments by automated Edman degradation and mass spectometry determination. BJ-PLA2 consists of 124 amino acid residues and has the structural features of snake venom class II phospholipases A2. Chemical modification with p-bromophenacylbromide caused complete loss of enzymatic activity and partially affected the platelet-aggregation-inhibiting activity of BJ-PLA2. | lld:pubmed |
| pubmed-article:10375395 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10375395 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10375395 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:10375395 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10375395 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:10375395 | pubmed:issn | 0003-9861 | lld:pubmed |
| pubmed-article:10375395 | pubmed:author | pubmed-author:CamargoA CAC | lld:pubmed |
| pubmed-article:10375395 | pubmed:author | pubmed-author:SantoroM LML | lld:pubmed |
| pubmed-article:10375395 | pubmed:author | pubmed-author:SampaioC ACA | lld:pubmed |
| pubmed-article:10375395 | pubmed:author | pubmed-author:AuerswaldE... | lld:pubmed |
| pubmed-article:10375395 | pubmed:author | pubmed-author:AssakuraM TMT | lld:pubmed |
| pubmed-article:10375395 | pubmed:author | pubmed-author:MenteleRR | lld:pubmed |
| pubmed-article:10375395 | pubmed:author | pubmed-author:SerranoS MSM | lld:pubmed |
| pubmed-article:10375395 | pubmed:author | pubmed-author:ReichlA PAP | lld:pubmed |
| pubmed-article:10375395 | pubmed:copyrightInfo | Copyright 1999 Academic Press. | lld:pubmed |
| pubmed-article:10375395 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10375395 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:10375395 | pubmed:volume | 367 | lld:pubmed |
| pubmed-article:10375395 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10375395 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10375395 | pubmed:pagination | 26-32 | lld:pubmed |
| pubmed-article:10375395 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:10375395 | pubmed:meshHeading | pubmed-meshheading:10375395... | lld:pubmed |
| pubmed-article:10375395 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10375395 | pubmed:articleTitle | A novel phospholipase A2, BJ-PLA2, from the venom of the snake Bothrops jararaca: purification, primary structure analysis, and its characterization as a platelet-aggregation-inhibiting factor. | lld:pubmed |
| pubmed-article:10375395 | pubmed:affiliation | Laboratory of Biochemistry and Biophysics and Laboratory of Pathophysiology Instituto Butantan, São Paulo, 05503-900, Brazil. s_serrano@hotmail.com | lld:pubmed |
| pubmed-article:10375395 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10375395 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:10375395 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10375395 | lld:pubmed |
