Linked Life Data

10373281

Source:http://linkedlifedata.com/resource/pubmed/id/10373281

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-8-2
pubmed:abstractText
To determine whether altered cellular immune response might mediate the increased health risks associated with social inhibition, we examined delayed type hypersensitivity (DTH) responses in 36 adults under conditions of low and high intensity social engagement. Participants come from a study of psychological factors in functional bowel disease and fibromyalgia. Under high engagement conditions, socially inhibited individuals showed significantly increased induration in response to intradermal tetanus toxoid. Under low engagement conditions, these individuals showed less pronounced DTH responses that did not differ in magnitude from those of uninhibited individuals. This pattern of results was found using two different measures of social inhibition and was independent of social inhibition's definition as a continuously distributed trait vs a discrete category. These data are consistent with the general hypothesis that social inhibition represents a predisposition to physiologic hyperresponsiveness that requires an exogenous social trigger for expression.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0889-1591
pubmed:author
pubmed:copyrightInfo
Copyright 1999 Academic Press.
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
187-200
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Socially inhibited individuals show heightened DTH response during intense social engagement.
pubmed:affiliation
Department of Medicine, University of California, Los Angeles, California 90095-1678, USA. coles@nicco.sscnet.ucla.edu
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't