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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
12
|
| pubmed:dateCreated |
1977-4-28
|
| pubmed:abstractText |
A further series of derivatives of maleopimaric acid, the maleopimaridyl morpholides, has been prepared and results on their protection against galactosamine-inducted liver damage in the rat are described. The compounds (3, 4, 8 and 10) were found to display the highest levels of hepato-protective activity in the series. Compound 8 (LD50 greater than 10 g/kg) which exhibited significant, dose-related protection at a daily dose in the range of 50-400 mg/kg, was selected for detailed investigation.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0004-4172
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
2190-2
|
| pubmed:dateRevised |
2009-11-19
|
| pubmed:meshHeading | |
| pubmed:year |
1976
|
| pubmed:articleTitle |
New hepato-protective agents. II. Maleopimaridyl morpholides.
|
| pubmed:publicationType |
Journal Article
|