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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1977-4-25
|
| pubmed:abstractText |
A sub-chronic study of 7-chloro-2,3-dihydro-3-hydroxy-1-methyl-5-phenyl-1H-1,4-benzodiazepin-2-one (temazepam, Euhypnos) at three dose levels was carried out in 30 healthy volunteers. A matching placebo was given before and after the 4 nights of active compound. The subjective response was measured by means of a sleep evaluation questionnaire, and the objective measurements used were the critical flicker fusion threshold and choice reaction time. A clear dose-response relationship was seen in the subjective and objective measurements with the three doses used. A rebound phenomenon was seen only at the high dose levels in two subjective measures, viz. getting to sleep and behaviour following waking.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0004-4172
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
2113-5
|
| pubmed:dateRevised |
2009-10-27
|
| pubmed:meshHeading | |
| pubmed:year |
1976
|
| pubmed:articleTitle |
A sub-chronic study of the subjective quality of sleep and psychological measures of performance on the morning following night time medication with temazepam.
|
| pubmed:publicationType |
Journal Article
|