Source:http://linkedlifedata.com/resource/pubmed/id/10372125
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1999-7-12
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pubmed:abstractText |
The fetal sheep competitive engraftment model of human hematopoietic stem cells (HSC) was used to evaluate the in vivo engraftment potential of human bone marrow CD34- Lin- cells. Transplantation of CD34- Lin- cells into primary hosts resulted in the long-term (> 1 year) engraftment and multilineage donor cell/progenitor expression with production of significant numbers of CD34+ cells. Secondary transplantation and limiting dilution studies confirmed the presence in human CD34- fraction of HSC with in vivo long-term engraftment and multilineage differentiation potentials.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0077-8923
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
872
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
220-31; discussion 231-2
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10372125-Animals,
pubmed-meshheading:10372125-Antigens, CD,
pubmed-meshheading:10372125-Antigens, CD34,
pubmed-meshheading:10372125-Biological Markers,
pubmed-meshheading:10372125-Bone Marrow Cells,
pubmed-meshheading:10372125-Cells, Cultured,
pubmed-meshheading:10372125-Fetus,
pubmed-meshheading:10372125-Graft Survival,
pubmed-meshheading:10372125-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:10372125-Hematopoietic Stem Cells,
pubmed-meshheading:10372125-Humans,
pubmed-meshheading:10372125-Sheep,
pubmed-meshheading:10372125-Transplantation, Heterologous
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pubmed:year |
1999
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pubmed:articleTitle |
Engraftment and multilineage expression of human bone marrow CD34- cells in vivo.
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pubmed:affiliation |
Department of Veterans Affairs Medical Center, University of Nevada Reno 89520, USA. zanjani@scs.unr.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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