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rdf:type |
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lifeskim:mentions |
umls-concept:C0019944,
umls-concept:C0021843,
umls-concept:C0021851,
umls-concept:C0027021,
umls-concept:C0027950,
umls-concept:C0032105,
umls-concept:C0441889,
umls-concept:C0543467,
umls-concept:C0683278,
umls-concept:C1155000,
umls-concept:C1548161
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pubmed:issue |
2
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pubmed:dateCreated |
1999-6-28
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pubmed:abstractText |
Myeloperoxidase (MPO) is a specific enzyme of neutrophil azurophilic granules with a strong oxidative activity. Thanks to a radioimmunoassay of equine myeloperoxidase, the authors have observed a significantly higher plasma level of MPO in horses operated for strangulation obstruction of the large intestine (n = 6) than in horses suffering from a non-strangulating displacement of the large intestine (n = 9). For the 2 groups, 3 phases were distinguished: reception (P1), intensive care (P2) and terminal phase (P3). The mean peak values of MPO for these phases were 121.6 ng/mL (P1), 168.6 ng/mL (P2), and 107.0 ng/mL (P3) for the non-strangulating group, and 242.6 ng/mL (P1); 426.0 ng/mL (P2), and 379.5 ng/mL (P3) for the strangulation group. The variations of the mean peak values of plasma MPO were significantly different between the 2 groups and between the different phases. A significant increase of the least square means of MPO was observed between P1 and P2. A significant decrease of the least square means of the number of circulating leukocytes was observed between P1 and P3. Polymorphonuclear neutrophil activation could play a major role in the pathogenesis of acute abdominal disease and endotoxic shock.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-1321589,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-1336991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-1456541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-1650868,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-17422234,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-1849540,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-1920254,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-2167032,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-2418905,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-2603371,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-2793543,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-3004270,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-3072553,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-3238878,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-3400917,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-5075520,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-6092199,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-6635660,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-7369591,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-7440357,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-7674213,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-7945255,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-7998704,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-8091626,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-8137924,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-9060452,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-9553712,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10369573-9764724
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0830-9000
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
63
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
142-7
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pubmed:dateRevised |
2010-9-13
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pubmed:meshHeading |
pubmed-meshheading:10369573-Acute Disease,
pubmed-meshheading:10369573-Animals,
pubmed-meshheading:10369573-Colonic Diseases,
pubmed-meshheading:10369573-Horse Diseases,
pubmed-meshheading:10369573-Horses,
pubmed-meshheading:10369573-Intensive Care,
pubmed-meshheading:10369573-Intestinal Obstruction,
pubmed-meshheading:10369573-Least-Squares Analysis,
pubmed-meshheading:10369573-Leukocyte Count,
pubmed-meshheading:10369573-Neutrophils,
pubmed-meshheading:10369573-Peroxidase
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pubmed:year |
1999
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pubmed:articleTitle |
Plasma myeloperoxidase level and polymorphonuclear leukocyte activation in horses suffering from large intestinal obstruction requiring surgery: preliminary results.
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pubmed:affiliation |
Anaesthésiologie générale, Pathologie chirugicale des grands animaux, Université de Liège, Sart Tilman, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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