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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
23
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pubmed:dateCreated |
1999-7-12
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pubmed:abstractText |
Thrombocytopenia frequently occurs early in the course of Gram-negative bacterial infections. Triflavin, an Arg-Gly-Asp-containing disintegrin, has been suggested to interfere with the interaction of fibrinogen with the glycoprotein IIb/IIIa complex. The present study was undertaken to determine whether triflavin could prevent thrombocytopenia in lipopolysaccharide (LPS)-treated rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
15
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pubmed:volume |
99
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3056-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10368125-Animals,
pubmed-meshheading:10368125-Aorta, Thoracic,
pubmed-meshheading:10368125-Bacteremia,
pubmed-meshheading:10368125-Crotalid Venoms,
pubmed-meshheading:10368125-Endothelium, Vascular,
pubmed-meshheading:10368125-Escherichia coli,
pubmed-meshheading:10368125-Lipopolysaccharides,
pubmed-meshheading:10368125-Liver,
pubmed-meshheading:10368125-Male,
pubmed-meshheading:10368125-Microscopy, Electron,
pubmed-meshheading:10368125-Nitrates,
pubmed-meshheading:10368125-Peptides,
pubmed-meshheading:10368125-Platelet Adhesiveness,
pubmed-meshheading:10368125-Platelet Aggregation Inhibitors,
pubmed-meshheading:10368125-Rats,
pubmed-meshheading:10368125-Rats, Sprague-Dawley,
pubmed-meshheading:10368125-Serotonin,
pubmed-meshheading:10368125-Thrombocytopenia,
pubmed-meshheading:10368125-Thromboxane A2
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pubmed:year |
1999
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pubmed:articleTitle |
Reduction in lipopolysaccharide-induced thrombocytopenia by triflavin in a rat model of septicemia.
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pubmed:affiliation |
Graduate Institute of Medical Sciences, Department of Anatomy, Taipei Medical College, Taipei, Taiwan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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