Linked Life Data

10368013

Source:http://linkedlifedata.com/resource/pubmed/id/10368013

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1999-8-20
pubmed:abstractText
Gamma-rays contribute 33% of the absorbed dose from an unfiltered 252Cf fission neutron source. To reduce this gamma-ray component and to enable radiobiological experiments at as high a dose rate as possible, Monte Carlo calculations for several filter materials (Al, Fe, Pb and concrete) have been made using MCNP neutron and photon transport code version 4a. A lead filter of thickness 4 cm was found to reduce the gamma-ray component to 6.7% of the total dose whilst reducing the neutron dose by only about 10%. Such a filter was installed at the MRC 252Cf neutron irradiation facility and dosimetric measurements were made using a TE-TE chamber and a 7LiF(Mg, Cu, P) TLD. Monte Carlo simulations agree with experimental measurements of neutron and gamma-ray doses within 6%. V79-4 Chinese hamster cells were irradiated with lead-filtered and unfiltered neutrons and also with 60Co gamma-rays at two dose rates. The survival fraction obtained for each radiation was consistent with the reduced gamma-ray dose. The relative biological effectiveness for neutrons alone, corrected for gamma-ray effects, was found to be 9.2 +/- 3.4 from the initial slopes and 3.1 +/- 0.5 at 10% survival, both relative to the acute gamma-rays.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0031-9155
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1207-18
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Reduction of the gamma-ray component from 252Cf fission neutron source--optimization for biological irradiations and comparison with MCNP code.
pubmed:affiliation
Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan. endos@ipc.hiroshima-u.ac.jp
pubmed:publicationType
Journal Article, Comparative Study