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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
1999-7-23
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pubmed:abstractText |
We have investigated the antigenicity of the C- and N-terminal halves of pIX of human adenovirus types 2 and 3 (Ad2 and Ad3) as well as their orientations in virions. We found that only the C-terminal halves of Ad2 pIX and Ad3 pIX reacted in a subgenus-specific manner by enzyme-linked immunosorbent assay and immunoblot analysis. Based on immunoelectron microscopy experiments, pIX in viral capsids appears to be positioned such that the C-terminal part of pIX constitutes the surface domain whereas the N terminus of the protein makes up the internal domain in icosahedral Ad capsids.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-1376769,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-1533079,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-1591615,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-2454713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-2583109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-3038533,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-354496,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-4020954,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-4046035,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-4057357,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-4068145,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-4139804,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-4955344,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-5420325,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-5675626,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-6250944,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-6266923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-6546423,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-6855599,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-6985473,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-7222481,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-7288921,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-7326748,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-7714051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-808902,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-8263936,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-8793835,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-8896246,
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http://linkedlifedata.com/resource/pubmed/commentcorrection/10364380-9765458
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0022-538X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6182-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:10364380-Adenoviruses, Human,
pubmed-meshheading:10364380-Animals,
pubmed-meshheading:10364380-Antibodies, Viral,
pubmed-meshheading:10364380-Antigens, Viral,
pubmed-meshheading:10364380-Binding Sites,
pubmed-meshheading:10364380-Capsid,
pubmed-meshheading:10364380-Capsid Proteins,
pubmed-meshheading:10364380-Gene Expression,
pubmed-meshheading:10364380-Humans,
pubmed-meshheading:10364380-Neutralization Tests,
pubmed-meshheading:10364380-Plasmids,
pubmed-meshheading:10364380-Rabbits,
pubmed-meshheading:10364380-Virion
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pubmed:year |
1999
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pubmed:articleTitle |
The subgenus-specific C-terminal region of protein IX is located on the surface of the adenovirus capsid.
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pubmed:affiliation |
Institute of Medical Microbiology, Ernst-Moritz-Arndt-University, D-17487 Greifswald, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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