rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
1999-7-22
|
pubmed:abstractText |
Benzolactam-V7 (3a), a simplified analogues of (-)-indolactam-V with twist-form conformation, was synthesized and evaluated as a new protein kinase C modulator. Both 3a and its-7-substituted analogue 3c showed weak binding activity to displace PDBU binding from recombinant PKCalpha.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0960-894X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
17
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1371-4
|
pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:10360738-Benzodiazepinones,
pubmed-meshheading:10360738-Binding, Competitive,
pubmed-meshheading:10360738-Isoenzymes,
pubmed-meshheading:10360738-Models, Molecular,
pubmed-meshheading:10360738-Molecular Structure,
pubmed-meshheading:10360738-Phorbol 12,13-Dibutyrate,
pubmed-meshheading:10360738-Protein Binding,
pubmed-meshheading:10360738-Protein Kinase C,
pubmed-meshheading:10360738-Protein Kinase C-alpha,
pubmed-meshheading:10360738-Recombinant Proteins
|
pubmed:year |
1999
|
pubmed:articleTitle |
Synthesis and protein kinase C binding activity of benzolactam-V7.
|
pubmed:affiliation |
State Key Laboratory of Bio-organic and Natural Product Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|