Source:http://linkedlifedata.com/resource/pubmed/id/10358959
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1999-7-6
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pubmed:abstractText |
123I-iodophenyl-9-methyl-pentadecanoic acid (9MPA) is a modified long-chain (15 carbons) fatty acid with a methyl branch on its 9 carbon location. Myocardial SPECT images (two sets, 10 min each) were obtained starting 10 min (early phase) and 50 min (delay phase) after the injection of 160 MBq 123I-9MPA at rest in 10 patients with acute myocardial infarction. The segmental myocardial uptake (% uptake) and clearance (% washout) from early to delay image were calculated by the SPECT data. ECG-gated myocardial SPECT with 99mTc-sestamibi was also performed and segmental left ventricular (LV) wall motion was evaluated using QGS (quantitative gated SPECT) program. The % uptake of LV segments with hypokinetic or akinetic wall motion were significantly lower than those with normokinesis (p < 0.01) for both early and delay phases. The % washout of hypokinetic segments were significantly lower than those of normokinetic regions (p < 0.01), while the % washout of akinetic segments were significantly higher than those of severely hypokinetic segments (p < 0.05). Thus, 123I-9MPA myocardial distribution and clearance thought to be associated with left ventricular regional wall motion.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Iodine Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Iodobenzenes,
http://linkedlifedata.com/resource/pubmed/chemical/Technetium Tc 99m Sestamibi,
http://linkedlifedata.com/resource/pubmed/chemical/iodofiltic acid
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0022-7854
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
241-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10358959-Fatty Acids,
pubmed-meshheading:10358959-Humans,
pubmed-meshheading:10358959-Iodine Radioisotopes,
pubmed-meshheading:10358959-Iodobenzenes,
pubmed-meshheading:10358959-Male,
pubmed-meshheading:10358959-Middle Aged,
pubmed-meshheading:10358959-Myocardial Infarction,
pubmed-meshheading:10358959-Technetium Tc 99m Sestamibi,
pubmed-meshheading:10358959-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:10358959-Ventricular Function, Left
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pubmed:year |
1999
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pubmed:articleTitle |
[Myocardial distribution of iodine-123-iodophenyl-9-methyl-pentadecanoic acid (9MPA) in patients with acute myocardial infarction: comparison with regional wall motion obtained from technetium-99m-sestamibi gated SPECT].
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pubmed:affiliation |
Department of Radiology, Nippon Medical School.
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
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