rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1999-7-6
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pubmed:abstractText |
Sulfonylurea receptors are classified as either high-affinity type 1 (SUR1) or low-affinity type 2 receptors (SUR2), and the gene expression of SURs has recently been demonstrated in kidney. However, functional data regarding a renal SUR are lacking. We previously demonstrated that mesangial cell (MC) gene and protein expression of extracellular matrix components were up-regulated by the sulfonylurea, tolazamide. After noting this biological response, we next sought to investigate the presence of a sulfonylurea receptor in rat MCs.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Glyburide,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channels, Inwardly...,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Drug,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfonylurea Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/sulfonylurea receptor
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2289-98
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10354277-ATP-Binding Cassette Transporters,
pubmed-meshheading:10354277-Animals,
pubmed-meshheading:10354277-Calcium,
pubmed-meshheading:10354277-Cell Line,
pubmed-meshheading:10354277-Gene Expression,
pubmed-meshheading:10354277-Glomerular Mesangium,
pubmed-meshheading:10354277-Glyburide,
pubmed-meshheading:10354277-Kinetics,
pubmed-meshheading:10354277-Potassium Channels,
pubmed-meshheading:10354277-Potassium Channels, Inwardly Rectifying,
pubmed-meshheading:10354277-RNA, Messenger,
pubmed-meshheading:10354277-Rats,
pubmed-meshheading:10354277-Rats, Inbred F344,
pubmed-meshheading:10354277-Receptors, Drug,
pubmed-meshheading:10354277-Sulfonylurea Compounds
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pubmed:year |
1999
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pubmed:articleTitle |
Characterization of the rat mesangial cell type 2 sulfonylurea receptor.
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pubmed:affiliation |
Department of Medicine, Division of Nephrology, Henry Ford Hospital, Detroit, Michigan, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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