Linked Life Data

10352131

Source:http://linkedlifedata.com/resource/pubmed/id/10352131

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1999-8-3
pubmed:abstractText
Criteria set by clinical services for referral for counselling and genetic testing are variable and often arbitrary. Empirical data and computer models are available to estimate the probability of being a mutation carrier, based on family and personal history. Surveys show that high proportions of women at risk of cancer and of women in the general population are interested in being tested, but this may be based on inflated perceptions of personal risk and limitations in understanding of the tests used and their implications. A high proportion of women with a positive family history have a greatly overestimated perception of their own risk, and even expert counselling has little impact on this. This risk perception may produce psychological distress and may reduce participation in screening programs. Counselling, while improving understanding, may also have little impact on prior interest in being tested. Interest in being tested relates to a wish to assess the risk for children, and hazards include potential health insurance discrimination. Testing may result in a reduction of psychological disturbance in those shown to be non-carriers, with little change in those shown to be carriers, but unwillingness to be tested may be related to psychological distress. The impact of publicity concerning genetic testing on perceptions of risk and on psychological disturbance, and the subsequent impact of counselling and intervention, require further assessment.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0228-8699
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
14-20
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Public health aspects of breast cancer gene testing in Canada. Part 2: selection for and effects of testing.
pubmed:affiliation
Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand. melwood@gandalf.otago.ac.nz
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't