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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1977-4-25
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pubmed:abstractText |
N-Nitroso-2,6-demethylmorpholine (NDMM) administered intraperitoneally to Syrian hamsters was metabolized to N-nitroso-bis(2-hydroxypropy)(2-oxopropyl)amine(HPOP) and N-nitroso-bis(2-hydroxpropyl)amine (BHP) which were identified in blood and urine. The potent pancreatic carcinogen N-nitroso-bis(2-oxoproply)amine was previously shown to form the same metabolites. Preliminary results indicate that NDMM also induces pancreatic and other tumors in Syrian hamsters, similar to those found following BHP treatment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
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pubmed:issn |
0304-3835
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
47-52
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:1035131-Aged,
pubmed-meshheading:1035131-Animals,
pubmed-meshheading:1035131-Cricetinae,
pubmed-meshheading:1035131-Humans,
pubmed-meshheading:1035131-Male,
pubmed-meshheading:1035131-Mesocricetus,
pubmed-meshheading:1035131-Morpholines,
pubmed-meshheading:1035131-Neoplasms, Experimental,
pubmed-meshheading:1035131-Nitrosamines,
pubmed-meshheading:1035131-Pancreatic Neoplasms
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pubmed:year |
1976
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pubmed:articleTitle |
Common metabolites of N-nitroso-2,6-dimethylomorpholine and N-nitroso-bis(2-oxopropyl)amine in the Syrian hamster.
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pubmed:publicationType |
Journal Article
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