Linked Life Data

10347963

Source:http://linkedlifedata.com/resource/pubmed/id/10347963

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1999-9-2
pubmed:abstractText
Effectiveness of non invasive positive pressure ventilation (NIPPV) was prospectively evaluated in 22 selected patients with acute respiratory failure, meeting criteria for orotracheal intubation and conventional mechanical ventilation. Patients were divided in two groups: group A (17 patients) with initial PaCO2 above 45 mm Hg and group B (5 patients) with initial PaCO2 below 45 mmHg. NIPPV was administered with 2 levels of pressure either by nasal or facial mask. Respiratory rate (RR), arterial blood pH, PaCO2 and PaO2/FiO2 were registered pretreatment, 1 hour and 24 hours after NIPPV. Statistical analysis was performed by ANOVA test, p < 0.05 was considered significant. RESULTS: In group A there was a reduction in RR (X +/- DS) from 31.2 +/- 8.2 to 24.7 +/- 8.2 at one hour (h) (p = 0.02) and to 23.4 +/- 6.5 at 24 hs (p = 0.01), pH change from 7.33 +/- 0.07 to 7.37 +/- 0.07 at one hour (p = 0.13) and to 7.40 +/- 0.07 at 24 hs (p = 0.01), a PaCO2 change from 69.5 +/- 19.6 to 57.8 +/- 16.9 at one hour (p = 0.06) and to 54 +/- 13 at 24 hs (p = 0.02), and PaO2/FiO2 change from 187.3 +/- 60.2 to 223.9 +/- 6.5 at one hour (p = 0.12) and to 245.8 +/- 75 at 24 hs (p = 0.03). In group B there was a change in RR from 33 +/- 16.3 to 26.6 +/- 12.5 at one hour (p = 0.46) and to 21.3 +/- 4.2 at 24 hs (p = 0.27), PaO2/FiO2 change from 113.4 +/- 31 to 137.8 +/- 57.2 at one hour (p = 0.44) and to 208.7 +/- 51.2 at 24 hs (p = 0.03). Only two patients in group A and one in group B were converted to conventional ARM. CONCLUSION: 1) NIPPV is a therapeutic alternative for selective patients with acute respiratory insufficiency and may reduce known morbidity of conventional mechanical ventilation. 2) In the group with hypercapnic acute respiratory failure the improvement in respiratory function begins with an immediate reduction in RR. Significant improvement in arterial blood gases usually occurs within 24 hours of NIPPV.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0025-7680
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
707-12
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[Non invasive ventilation in acute respiratory insufficiency: an alternative].
pubmed:affiliation
Servicio de Neumonología y Terapia Intensiva, Hospital Privado, Centro Médico de Córdoba, Argentina.
pubmed:publicationType
Journal Article, Clinical Trial, English Abstract