Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1977-2-24
|
pubmed:abstractText |
Neonatal rats were given s.c. injections of 1 mg of hydrocortisone acetate, and the effect on the subsequent development of the pituitary-adrenal response to ether stress and the development of the circadian rhythm in adrenal and serum corticosterone (B) was investigated. Following exposure to ether, adrenal steroids were elevated in 11-day-old controls. The response did not appear in treated animals until 25 days. At this age, the time-course of response to ether in the adrenal was more sluggish in hormone-treated rats. After stress, serum corticoids were high in controls at 20 days; however, this rise did not appear in treated rats until 25 days. Serum corticoids, 5-60 min after ether, tended to be lower in 25-day-old runts than in controls. The diurnal rhythm in serum B first appeared in controls at 27 days and in treated animals at 30 days. The rhythm in adrenal corticoids appeared in both groups at 30 days.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0028-3835
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
49-57
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:1034242-Age Factors,
pubmed-meshheading:1034242-Animals,
pubmed-meshheading:1034242-Animals, Newborn,
pubmed-meshheading:1034242-Circadian Rhythm,
pubmed-meshheading:1034242-Corticosterone,
pubmed-meshheading:1034242-Ether, Ethyl,
pubmed-meshheading:1034242-Hydrocortisone,
pubmed-meshheading:1034242-Rats,
pubmed-meshheading:1034242-Stress, Physiological,
pubmed-meshheading:1034242-Time Factors
|
pubmed:year |
1976
|
pubmed:articleTitle |
Neonatal hydrocortisone: effect of the development of the stress response and the diurnal rhythm of corticosterone.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|