10340921

Source:http://linkedlifedata.com/resource/pubmed/id/10340921

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017431, umls-concept:C0028978, umls-concept:C0086418, umls-concept:C0442113, umls-concept:C0449438, umls-concept:C1280500, umls-concept:C1332828
pubmed:issue	5
pubmed:dateCreated	1999-5-27
pubmed:abstractText	Omeprazole is metabolized by genetically determined S-mephenytoin 4'-hydroxylase (CYP2C19) in the liver. This study aimed to determine whether the effect of omeprazole on intragastric pH depends on CYP2C19 genotype status.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0372741
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Ulcer Agents, http://linkedlifedata.com/resource/pubmed/chemical/Aryl Hydrocarbon Hydroxylases, http://linkedlifedata.com/resource/pubmed/chemical/CYP2C19 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Gastrins, http://linkedlifedata.com/resource/pubmed/chemical/Mixed Function Oxygenases, http://linkedlifedata.com/resource/pubmed/chemical/Omeprazole
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	0009-9236
pubmed:author	pubmed-author:FurutaTT, pubmed-author:HanaiHH, pubmed-author:IshizakiTT, pubmed-author:KanekoEE, pubmed-author:KimuraMM, pubmed-author:KosugeKK, pubmed-author:NishimotoMM, pubmed-author:OhashiKK, pubmed-author:TakashimaMM, pubmed-author:ZhaoX JXJ
pubmed:issnType	Print
pubmed:volume	65
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	552-61
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:10340921-Adult, pubmed-meshheading:10340921-Anti-Ulcer Agents, pubmed-meshheading:10340921-Area Under Curve, pubmed-meshheading:10340921-Aryl Hydrocarbon Hydroxylases, pubmed-meshheading:10340921-Asian Continental Ancestry Group, pubmed-meshheading:10340921-Cytochrome P-450 Enzyme System, pubmed-meshheading:10340921-Enzyme Inhibitors, pubmed-meshheading:10340921-Female, pubmed-meshheading:10340921-Gastrins, pubmed-meshheading:10340921-Genotype, pubmed-meshheading:10340921-Helicobacter Infections, pubmed-meshheading:10340921-Helicobacter pylori, pubmed-meshheading:10340921-Humans, pubmed-meshheading:10340921-Hydrogen-Ion Concentration, pubmed-meshheading:10340921-Japan, pubmed-meshheading:10340921-Male, pubmed-meshheading:10340921-Mixed Function Oxygenases, pubmed-meshheading:10340921-Omeprazole, pubmed-meshheading:10340921-Polymerase Chain Reaction, pubmed-meshheading:10340921-Polymorphism, Restriction Fragment Length, pubmed-meshheading:10340921-Reference Values, pubmed-meshheading:10340921-Stomach
pubmed:year	1999
pubmed:articleTitle	CYP2C19 genotype status and effect of omeprazole on intragastric pH in humans.
pubmed:affiliation	First Department of Medicine, Hamamatsu University School of Medicine, Japan.
pubmed:publicationType	Journal Article, Clinical Trial, Controlled Clinical Trial, Research Support, Non-U.S. Gov't