|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1999-6-8
|
|
pubmed:abstractText |
Hemorrhagic shock is associated with lactic acidosis and increased plasma catecholamines. Skeletal muscle increases lactate production under aerobic conditions in response to epinephrine, and this effect is blocked by ouabain, a specific inhibitor of the cell membrane Na+/K+ pump. In this study, we tested whether adrenergic antagonists can block lactate production during shock.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0022-5282
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
46
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
873-80
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:10338406-Acidosis, Lactic,
pubmed-meshheading:10338406-Adrenergic Antagonists,
pubmed-meshheading:10338406-Adrenergic alpha-Antagonists,
pubmed-meshheading:10338406-Adrenergic beta-Antagonists,
pubmed-meshheading:10338406-Animals,
pubmed-meshheading:10338406-Epinephrine,
pubmed-meshheading:10338406-Hindlimb,
pubmed-meshheading:10338406-Lactic Acid,
pubmed-meshheading:10338406-Male,
pubmed-meshheading:10338406-Muscle, Skeletal,
pubmed-meshheading:10338406-Norepinephrine,
pubmed-meshheading:10338406-Phenoxybenzamine,
pubmed-meshheading:10338406-Propranolol,
pubmed-meshheading:10338406-Rats,
pubmed-meshheading:10338406-Rats, Sprague-Dawley,
pubmed-meshheading:10338406-Regional Blood Flow,
pubmed-meshheading:10338406-Resuscitation,
pubmed-meshheading:10338406-Shock, Hemorrhagic
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
Adrenergic antagonists reduce lactic acidosis in response to hemorrhagic shock.
|
|
pubmed:affiliation |
Division of Trauma and Critical Care, University of Cincinnati College of Medicine, Ohio, USA. fred.luchette@uc.edu
|
|
pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
