rdf:type |
|
lifeskim:mentions |
umls-concept:C0006141,
umls-concept:C0007102,
umls-concept:C0015737,
umls-concept:C0021853,
umls-concept:C0030705,
umls-concept:C0085533,
umls-concept:C0543467,
umls-concept:C1274040,
umls-concept:C1446468,
umls-concept:C1510810,
umls-concept:C1522673,
umls-concept:C1709701
|
pubmed:issue |
5
|
pubmed:dateCreated |
1999-5-27
|
pubmed:abstractText |
Although the benefit from adjuvant chemotherapy has been clearly established in patients with Dukes' C colon cancer, such benefit has been questioned in patients with Dukes' B disease. To determine whether patients with Dukes' B disease benefit from adjuvant chemotherapy and to evaluate the magnitude of the benefit, compared with that observed in Dukes' C patients, we examined the relative efficacy of adjuvant chemotherapy according to Dukes' stage in four sequential National Surgical Adjuvant Breast and Bowel Project trials (C-01, C-02, C-03, and C-04) that compared different adjuvant chemotherapy regimens with each other or with no adjuvant treatment.
|
pubmed:grant |
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0732-183X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
17
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1349-55
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10334518-Adenocarcinoma,
pubmed-meshheading:10334518-Antidotes,
pubmed-meshheading:10334518-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:10334518-Chemotherapy, Adjuvant,
pubmed-meshheading:10334518-Colonic Neoplasms,
pubmed-meshheading:10334518-Fluorouracil,
pubmed-meshheading:10334518-Humans,
pubmed-meshheading:10334518-Leucovorin,
pubmed-meshheading:10334518-Neoplasm Staging,
pubmed-meshheading:10334518-Randomized Controlled Trials as Topic,
pubmed-meshheading:10334518-Semustine,
pubmed-meshheading:10334518-Survival Analysis,
pubmed-meshheading:10334518-Vincristine
|
pubmed:year |
1999
|
pubmed:articleTitle |
Comparative efficacy of adjuvant chemotherapy in patients with Dukes' B versus Dukes' C colon cancer: results from four National Surgical Adjuvant Breast and Bowel Project adjuvant studies (C-01, C-02, C-03, and C-04)
|
pubmed:affiliation |
National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistical Centers, Pittsburgh, PA 15212, USA.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't,
Meta-Analysis
|