Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1977-1-25
pubmed:abstractText
The association of actin filaments with membranes is an important feature in the motility of nonmuscle cells. We investigated the role of membrane particles in the attachment of actin filaments to membranes in those systems in which the attachment site can be identified. Freeze fractures through the end-on attachment site of the acrosomal filament bundles in Mytilus (mussel) and Limulus (horseshoe crab) sperm and the attachment site of the microvillar filament bundles in the brush border of intestinal epithelial cells were examined. There are no particles on the P face of the membrane at these sites in the sperm systems and generally none at these sites in microvilli. In microvilli, the actin filaments are also attached along their lengths to the membrane by bridges. When the isolated brush border is incubated in high concentrations of Mg++ (15 mM), the actin filaments form paracrystals and, as a result, the bridges are in register (330 A period). Under these conditions, alignment of the particles on the P face of the membrane into circumferential bands also occurs. However, these bands are generally separated by 800-900 A, indicating that all the bridges cannot be directly attached to membrane particles. Thus membrane particles are not directly involved in the attachment of actin filaments to membranes.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-1059087, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-1091302, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-1103304, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-1117029, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-1127014, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-1166299, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-1176533, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-1202021, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-127386, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-14287177, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4101164, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4125372, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4253329, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4269685, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4273099, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4333023, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4356568, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4363961, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4368822, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4528433, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4567783, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4571550, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4572924, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4578441, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4782838, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4937093, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4944636, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-4998250, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-5344150, http://linkedlifedata.com/resource/pubmed/commentcorrection/1033184-6080043
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0021-9525
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
402-16
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Actin filament-membrane attachment: are membrane particles involved?
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.