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pubmed-article:10327208pubmed:abstractTextLewy bodies and coarse Lewy neurites are the pathological hallmarks of degenerating neurons in the brains of patients suffering from Parkinson's disease (PD). Recently, the presynaptic protein alpha-synuclein was shown to be a major component of Lewy bodies and Lewy neurites. This study demonstrates for the first time that extensive and thin alpha-synuclein-immunoreactive inclusions are present in the axonal processes of neurons.lld:pubmed
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pubmed-article:10327208pubmed:articleTitleExtensive axonal Lewy neurites in Parkinson's disease: a novel pathological feature revealed by alpha-synuclein immunocytochemistry.lld:pubmed
pubmed-article:10327208pubmed:affiliationDepartment of Anatomy, J.W. Goethe University, Frankfurt/Main, Germany. braak@em.uni-frankfurt.delld:pubmed
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