Source:http://linkedlifedata.com/resource/pubmed/id/10327208
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1999-7-14
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pubmed:abstractText |
Lewy bodies and coarse Lewy neurites are the pathological hallmarks of degenerating neurons in the brains of patients suffering from Parkinson's disease (PD). Recently, the presynaptic protein alpha-synuclein was shown to be a major component of Lewy bodies and Lewy neurites. This study demonstrates for the first time that extensive and thin alpha-synuclein-immunoreactive inclusions are present in the axonal processes of neurons.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
9
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pubmed:volume |
265
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
67-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10327208-Axons,
pubmed-meshheading:10327208-Humans,
pubmed-meshheading:10327208-Immunohistochemistry,
pubmed-meshheading:10327208-Lewy Bodies,
pubmed-meshheading:10327208-Nerve Tissue Proteins,
pubmed-meshheading:10327208-Neurites,
pubmed-meshheading:10327208-Parkinson Disease,
pubmed-meshheading:10327208-Synucleins,
pubmed-meshheading:10327208-alpha-Synuclein
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pubmed:year |
1999
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pubmed:articleTitle |
Extensive axonal Lewy neurites in Parkinson's disease: a novel pathological feature revealed by alpha-synuclein immunocytochemistry.
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pubmed:affiliation |
Department of Anatomy, J.W. Goethe University, Frankfurt/Main, Germany. braak@em.uni-frankfurt.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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