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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1978-3-10
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pubmed:abstractText |
The surface properties of vincristine-colchicine sensitive and resistant L1210 leukaemic cells have been studied using concanavalin A mediated agglutination assay as well as electron microscopic visualization of concanavalin A receptors. 3H-colchicine uptake by the sensitive and resistant lines has also been compared. The resistant L1210 leukaemic cells proved less agglutinable than the sensitive ones at the same concanavalin A concentration. Previous treatments with either colchicine, vincristine or chlorpromazine caused a marked decrease in the agglutinability of the sensitive L1210 leukaemic cells, while agglutination of the resistant ones was lowered slightly by the same treatments. The 3H-colchicine uptake of the sensitive cells was three times higher than that of the resistant ones.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0001-6217
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
297-305
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1032277-Animals,
pubmed-meshheading:1032277-Cell Membrane,
pubmed-meshheading:1032277-Colchicine,
pubmed-meshheading:1032277-Drug Resistance,
pubmed-meshheading:1032277-Leukemia L1210,
pubmed-meshheading:1032277-Mice,
pubmed-meshheading:1032277-Receptors, Concanavalin A,
pubmed-meshheading:1032277-Surface Properties
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pubmed:year |
1976
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pubmed:articleTitle |
Cell surface properties of L1210 leukaemia cells.
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pubmed:publicationType |
Journal Article,
In Vitro
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