Source:http://linkedlifedata.com/resource/pubmed/id/10321490
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1999-6-23
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pubmed:abstractText |
Sciatic nerve resection leaving a 15 mm gap could not be repaired by bridging the stumps with a silicone tube prefilled with a laminin gel. However, when purified olfactory ensheathing cells (EC) were added to the gel filling the tube, successful axonal regeneration was observed in 50% of rats. With 12 mm gaps, regeneration occurred in 79% of rats with transplanted EC compared with 60% of those receiving collagen gel alone. Therefore, ECs help repair severe peripheral nerve injuries, in addition to their ability to promote axonal regeneration within the central nervous system.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0959-4965
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
6
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1097-101
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10321490-Action Potentials,
pubmed-meshheading:10321490-Animals,
pubmed-meshheading:10321490-Axons,
pubmed-meshheading:10321490-Collagen,
pubmed-meshheading:10321490-Gels,
pubmed-meshheading:10321490-Muscle, Skeletal,
pubmed-meshheading:10321490-Nerve Regeneration,
pubmed-meshheading:10321490-Neurology,
pubmed-meshheading:10321490-Neurons,
pubmed-meshheading:10321490-Olfactory Bulb,
pubmed-meshheading:10321490-Rats,
pubmed-meshheading:10321490-Rats, Wistar,
pubmed-meshheading:10321490-Reaction Time,
pubmed-meshheading:10321490-Reference Values,
pubmed-meshheading:10321490-Sciatic Nerve
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pubmed:year |
1999
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pubmed:articleTitle |
Olfactory bulb ensheathing cells enhance peripheral nerve regeneration.
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pubmed:affiliation |
Department of Cell Biology and Physiology, Faculty of Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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