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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1979-2-12
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pubmed:abstractText |
Human peripheral blood lymphocytes (HPBL) were sensitized to mitomycin-treated murine spleen cells and mitomycin-treated mastocytoma P-815. A DNA proliferative response occurred to both cell types. The sensitized HPBL lysed chromium-51-labelled mastocytoma P-815 cells in a cell-mediated cytotoxicity assay (CMC). Evidence is presented that this human-murine xenogeneic system involves T cell response with specificity in CMC mainly toward H-2 antigens. DBA/2 splenocytes were superior to mastocytoma cells as sensitizers in the xenogeneic DNA proliferative assay.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0022-1759
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
9-18
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:102702-Animals,
pubmed-meshheading:102702-Cytotoxicity, Immunologic,
pubmed-meshheading:102702-Humans,
pubmed-meshheading:102702-Immunity, Cellular,
pubmed-meshheading:102702-Lymphocyte Activation,
pubmed-meshheading:102702-Lymphocytes,
pubmed-meshheading:102702-Mast-Cell Sarcoma,
pubmed-meshheading:102702-Mice,
pubmed-meshheading:102702-Mice, Inbred BALB C,
pubmed-meshheading:102702-Mice, Inbred C57BL,
pubmed-meshheading:102702-Mice, Inbred DBA,
pubmed-meshheading:102702-Mitomycins,
pubmed-meshheading:102702-Spleen
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pubmed:year |
1978
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pubmed:articleTitle |
Xenogenic response of human peripheral blood lymphocytes against murine cells in vitro.
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pubmed:publicationType |
Journal Article
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