Linked Life Data

1026201

Source:http://linkedlifedata.com/resource/pubmed/id/1026201

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-3
pubmed:dateCreated
1977-6-22
pubmed:abstractText
Experiments intended to correlate the biochemical action of erythropoietin and testosterone on marrow cells are presented. Both hormones seem to act at different cytological and biochemical levels. Erythropoietin triggers the erythropoietic phenomenon acting on the Erythropoietin-Sensitive Cells. Inducing the synthesis of a large size RNA, (85S) which after a ribonuclease-dependent processing mechanism generates the informational RNA (9S) required for hemoglobin synthesis. Testosterone acts directly on bone marrow (probably at the level of polychromatophylic erythroblasts) enhancing the synthesis of ribosomal RNA or its precursors and stimulates a nuclear ribonuclease which might represent a control mechanism on the processing of high molecular weight RNAs. It is postulated that erythropoietin and testosterone act synergistically to create the biochemical machinery for hemoglobin synthesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0004-0533
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
35-40
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Hormone action on the cell nucleus: effect of erythropoietin and testosterone on bone marrow.
pubmed:publicationType
Journal Article