Source:http://linkedlifedata.com/resource/pubmed/id/10233642
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1999-7-29
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pubmed:abstractText |
A 3-month-old male infant was referred to our department with a generalized brown, thickened leathery skin and blisters which had been present since birth; the blisters developed recurrently at sites of minor trauma, healing without scar formation, although Darier's sign was positive. Microscopically, biopsy specimens showed a dense dermal band-like infiltrate with mast cells, whereas a biopsy from a vesicle showed subepidermal bulla formation. Physical examination did not reveal any systemic involvement with mastocytosis and the patient was treated with cyproheptadine, which has considerable anti-serotonin activity and, interestingly, reduced the degree of blistering; this treatment might therefore be tried in other cases.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0307-6938
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
16-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading | |
pubmed:year |
1999
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pubmed:articleTitle |
Diffuse cutaneous mastocytosis responding to cyproheptadine.
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pubmed:affiliation |
Department of Dermatology, Osaka Medical College, Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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