Linked Life Data

10225331

Source:http://linkedlifedata.com/resource/pubmed/id/10225331

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1999-6-28
pubmed:abstractText
Several types of design have been used to identify neurocognitive measures that indicate vulnerability to schizophrenia rather than the presence of the illness. These designs include studies of first-degree relatives of patients, studies of patients in symptomatic remission, and studies of subjects who are considered to be prone to psychosis. The backward masking procedure is one promising indicator of vulnerability to schizophrenia. Backward masking is a procedure in which identification of an initial stimulus (the target) is disrupted by a later stimulus (the mask). Schizophrenic patients show performance deficits on backward masking. Unaffected siblings of patients, remitted patients, and individuals prone to psychosis also show performance deficits on backward masking. This pattern of results suggests that backward masking is a promising indicator of vulnerability to schizophrenia. It provides an alternative phenotype for schizophrenia that is separate from the disorder. The composite nature of masking procedures helps investigators to parse a performance deficit into its smallest meaningful elements and relate them to vulnerability to schizophrenia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0065-1591
pubmed:author
pubmed:issnType
Print
pubmed:volume
395
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
34-40
pubmed:dateRevised
2008-2-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Backward masking performance as an indicator of vulnerability to schizophrenia.
pubmed:affiliation
UCLA Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA, USA.
pubmed:publicationType
Journal Article, Review