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rdf:type |
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lifeskim:mentions |
umls-concept:C0003835,
umls-concept:C0010055,
umls-concept:C0023516,
umls-concept:C0030685,
umls-concept:C0030705,
umls-concept:C0178645,
umls-concept:C0180860,
umls-concept:C0391871,
umls-concept:C0581406,
umls-concept:C0680255,
umls-concept:C1280500,
umls-concept:C1283071,
umls-concept:C1518988,
umls-concept:C1522664,
umls-concept:C1536078,
umls-concept:C1546637,
umls-concept:C1550638,
umls-concept:C1704449,
umls-concept:C1704684,
umls-concept:C1947941,
umls-concept:C1963578
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pubmed:issue |
4
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pubmed:dateCreated |
1999-6-18
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pubmed:abstractText |
Proteolytic enzymes and oxygen free radicals released from activated leucocytes contribute significantly to the organ dysfunction associated with cardiopulmonary bypass. Leucocyte depletion during extracorporeal circulation should reduce the release of these toxic compounds and thereby improve postbypass myocardial and pulmonary function. Recently, a leucocyte-specific arterial line filter to achieve leucocyte depletion during clinical perfusion has become commercially available. The aim of this study, therefore, was to evaluate the influence of the leucocyte depleting arterial line filter on proteolytic enzyme release, oxygen free radical release and postbypass pulmonary and myocardial function in patients undergoing bypass surgery.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/C-Reactive Protein,
http://linkedlifedata.com/resource/pubmed/chemical/Cardiotonic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Creatine Kinase,
http://linkedlifedata.com/resource/pubmed/chemical/Free Radicals,
http://linkedlifedata.com/resource/pubmed/chemical/Isoenzymes,
http://linkedlifedata.com/resource/pubmed/chemical/Malondialdehyde,
http://linkedlifedata.com/resource/pubmed/chemical/Oxygen,
http://linkedlifedata.com/resource/pubmed/chemical/Pancreatic Elastase,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Hydrolases,
http://linkedlifedata.com/resource/pubmed/chemical/Reactive Oxygen Species,
http://linkedlifedata.com/resource/pubmed/chemical/Troponin I
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0001-5172
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
452-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10225080-Aged,
pubmed-meshheading:10225080-C-Reactive Protein,
pubmed-meshheading:10225080-Cardiopulmonary Bypass,
pubmed-meshheading:10225080-Cardiotonic Agents,
pubmed-meshheading:10225080-Coronary Artery Bypass,
pubmed-meshheading:10225080-Creatine Kinase,
pubmed-meshheading:10225080-Extracorporeal Circulation,
pubmed-meshheading:10225080-Female,
pubmed-meshheading:10225080-Filtration,
pubmed-meshheading:10225080-Follow-Up Studies,
pubmed-meshheading:10225080-Free Radicals,
pubmed-meshheading:10225080-Heart,
pubmed-meshheading:10225080-Humans,
pubmed-meshheading:10225080-Isoenzymes,
pubmed-meshheading:10225080-Leukapheresis,
pubmed-meshheading:10225080-Leukocyte Count,
pubmed-meshheading:10225080-Lung,
pubmed-meshheading:10225080-Male,
pubmed-meshheading:10225080-Malondialdehyde,
pubmed-meshheading:10225080-Middle Aged,
pubmed-meshheading:10225080-Oxygen,
pubmed-meshheading:10225080-Pancreatic Elastase,
pubmed-meshheading:10225080-Peptide Hydrolases,
pubmed-meshheading:10225080-Prospective Studies,
pubmed-meshheading:10225080-Reactive Oxygen Species,
pubmed-meshheading:10225080-Surgical Procedures, Elective,
pubmed-meshheading:10225080-Troponin I
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pubmed:year |
1999
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pubmed:articleTitle |
Effects of a leucocyte depleting arterial line filter on perioperative proteolytic enzyme and oxygen free radical release in patients undergoing aortocoronary bypass surgery.
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pubmed:affiliation |
Department of Anaesthesia & Intensive Care Medicine, University of Innsbruck, School of Medicine, Austria.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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