Linked Life Data

10222773

Source:http://linkedlifedata.com/resource/pubmed/id/10222773

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1999-6-1
pubmed:abstractText
This review summarizes the current progress in the research on the function of ataxin-2 and the mechanism of pathogenesis for SCA2. Recent studies on genomic structure of the human gene for SCA2 and on the mouse homolog of the SCA2 gene have shed light on the molecular mechanism of pathogenesis of SCA2. Analysis of the expression pattern of ataxin-2 in human brain revealed that both wild-type and mutant form of ataxin-2 were expressed and the wild-type ataxin-2 was localized in the cytoplasm with strong labeling of Purkinje cells and that intranuclear inclusions were not seen in SCA2 brain.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0047-1852
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
822-4
pubmed:dateRevised
2011-7-27
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
[The function of spinocerebellar ataxia type 2 (SCA2) gene product, ataxin-2 and the mechanism of pathogenesis for SCA2].
pubmed:affiliation
Department of Neurology, Sado General Hospital.
pubmed:publicationType
Journal Article, English Abstract, Review