Linked Life Data

10222219

Source:http://linkedlifedata.com/resource/pubmed/id/10222219

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-6-15
pubmed:abstractText
Nitric oxide (NO) is a free radical molecule endogenously produced by NO synthases that may play a critical role in inflammation. It inhibits cell proliferation and may be involved in the induction of apoptosis in various cellular models. Recently, the presence of apoptotic cells was reported in the synovium of osteoarthritic (OA) patients. The aim of this study was to determine whether synovial fibroblasts are target cells for NO-induced apoptosis. The expression of p53 protein was also studied to evaluate the ability of synovial cells to repair DNA fragmentation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1063-4584
pubmed:author
pubmed:copyrightInfo
Copyright 1999 OsteoArthritis Research Society International.
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
203-13
pubmed:dateRevised
2010-3-24
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Apoptosis induced by nitric oxide is associated with nuclear p53 protein expression in cultured osteoarthritic synoviocytes.
pubmed:affiliation
Laboratoire de Biochimie A, Hôpital Cochin, Université René Descartes, 27 rue du fg St Jacques, Paris, 75014, France.
pubmed:publicationType
Journal Article