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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1999-4-29
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pubmed:abstractText |
It has already been reported that loss of heterozygosity (LOH) on chromosome 1p is frequent in a variety of human cancers. This finding implies the presence of some important tumour suppressor genes in this region. p73, a candidate tumour suppressor gene identified recently in chromosome band 1p36.33, encodes a protein highly homologous to p53. To investigate the role of the p73 gene in human carcinogenesis, we studied genetic alterations of this gene in various human cancers.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0748-7983
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pubmed:author |
pubmed-author:AbeTT,
pubmed-author:FukushigeSS,
pubmed-author:FurukawaTT,
pubmed-author:HamRR,
pubmed-author:HorieMM,
pubmed-author:MakinoNN,
pubmed-author:MatsunoSS,
pubmed-author:NakagawaraAA,
pubmed-author:NimuraYY,
pubmed-author:SakuradaAA,
pubmed-author:SatoMM,
pubmed-author:SembaSS,
pubmed-author:ShiibaKK,
pubmed-author:TakahashiHH
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
194-8
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pubmed:dateRevised |
2007-7-2
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pubmed:meshHeading |
pubmed-meshheading:10218465-Alleles,
pubmed-meshheading:10218465-Breast Neoplasms,
pubmed-meshheading:10218465-Chromosomes, Human, Pair 1,
pubmed-meshheading:10218465-DNA-Binding Proteins,
pubmed-meshheading:10218465-Digestive System Neoplasms,
pubmed-meshheading:10218465-Genes, Tumor Suppressor,
pubmed-meshheading:10218465-Humans,
pubmed-meshheading:10218465-Lung Neoplasms,
pubmed-meshheading:10218465-Mutation, Missense,
pubmed-meshheading:10218465-Neoplasms,
pubmed-meshheading:10218465-Neuroblastoma,
pubmed-meshheading:10218465-Nuclear Proteins,
pubmed-meshheading:10218465-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:10218465-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:10218465-Tumor Suppressor Proteins
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pubmed:year |
1999
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pubmed:articleTitle |
Infrequent somatic mutations of the p73 gene in various human cancers.
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pubmed:affiliation |
Department of Molecular Pathology, Tohoku University School of Medicine, Sendai, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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