Source:http://linkedlifedata.com/resource/pubmed/id/10217588
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
15-16
|
| pubmed:dateCreated |
1999-7-8
|
| pubmed:abstractText |
We conducted a randomized, double-blind trial to evaluate the safety and tolerability of a live attenuated cold adapted trivalent intranasal influenza vaccine, FluMist, compared with intranasal placebo when given in addition to a licensed trivalent injected inactivated influenza vaccine (TIV). The study population consisted of persons 65 years of age and older with chronic cardiovascular or pulmonary conditions or diabetes mellitus. During the 7 days post-vaccination, sore throat was reported on at least one day by 15% (15/100) of FluMist recipients compared with 2% (2/100) of intranasal placebo recipients (p = 0.001). No other reactogenicity symptom was statistically associated with receipt of FluMist. Among this group, FluMist was safe and well tolerated when administered with TIV.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0264-410X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
9
|
| pubmed:volume |
17
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1905-9
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:10217588-Administration, Intranasal,
pubmed-meshheading:10217588-Aged,
pubmed-meshheading:10217588-Body Temperature,
pubmed-meshheading:10217588-Cardiovascular Diseases,
pubmed-meshheading:10217588-Chronic Disease,
pubmed-meshheading:10217588-Diabetes Mellitus,
pubmed-meshheading:10217588-Double-Blind Method,
pubmed-meshheading:10217588-Female,
pubmed-meshheading:10217588-Humans,
pubmed-meshheading:10217588-Influenza Vaccines,
pubmed-meshheading:10217588-Injections,
pubmed-meshheading:10217588-Lung Diseases,
pubmed-meshheading:10217588-Male,
pubmed-meshheading:10217588-Pharyngitis,
pubmed-meshheading:10217588-Prospective Studies,
pubmed-meshheading:10217588-Time Factors,
pubmed-meshheading:10217588-Vaccination,
pubmed-meshheading:10217588-Vaccines, Attenuated,
pubmed-meshheading:10217588-Vaccines, Inactivated
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Safety of a trivalent live attenuated intranasal influenza vaccine, FluMist, administered in addition to parenteral trivalent inactivated influenza vaccine to seniors with chronic medical conditions.
|
| pubmed:affiliation |
Immunization Studies Program, Center for Health Studies, Group Health Cooperative of Puget Sound, WA, USA. lajack@u.washington.edu
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|