Source:http://linkedlifedata.com/resource/pubmed/id/10217550
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1999-7-1
|
| pubmed:abstractText |
This study examined plasma cotinine replacement levels of 56 outpatient smokers administered a 21 mg/day transdermal nicotine patch (Nicoderm CQ ). The percentage of cotinine replacement ranged from 35 to 232% (mean 107%; median 90.5%). Four subject variables were found to be significantly correlated with percentage of cotinine replacement-baseline cotinine level, prior quit attempts, gender, and the Fagerström Tolerance Questionnaire score. A two-variable model consisting of baseline cotinine level and gender provided the most powerful predictor combination. The percentage of cotinine replacement was not predictive of post-treatment smoking. The relatively high levels of cotinine replacement obtained using the Nicoderm CQ 21 mg/day patch suggest cautious use of higher dose treatment with this particular patch.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0376-8716
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
54
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
111-6
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:10217550-Administration, Cutaneous,
pubmed-meshheading:10217550-Adult,
pubmed-meshheading:10217550-Biological Markers,
pubmed-meshheading:10217550-Chi-Square Distribution,
pubmed-meshheading:10217550-Cholinergic Agents,
pubmed-meshheading:10217550-Cotinine,
pubmed-meshheading:10217550-Double-Blind Method,
pubmed-meshheading:10217550-Drug Administration Schedule,
pubmed-meshheading:10217550-Female,
pubmed-meshheading:10217550-Humans,
pubmed-meshheading:10217550-Logistic Models,
pubmed-meshheading:10217550-Male,
pubmed-meshheading:10217550-Middle Aged,
pubmed-meshheading:10217550-Nicotine,
pubmed-meshheading:10217550-Sex Factors,
pubmed-meshheading:10217550-Smoking Cessation,
pubmed-meshheading:10217550-Substance Withdrawal Syndrome,
pubmed-meshheading:10217550-Tobacco Use Disorder,
pubmed-meshheading:10217550-Treatment Outcome
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Cotinine replacement levels for a 21 mg/day transdermal nicotine patch in an outpatient treatment setting.
|
| pubmed:affiliation |
University of Pennsylvania, School of Medicine, Philadelphia 19104, USA.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial
|