Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1999-5-10
pubmed:abstractText
As in other hematological malignancies, the achievement of a complete remission (CR) is important in multiple myeloma but is still based on common cytological and electrophoretic criteria. In this report, we studied 14 patients who achieved an apparent CR following high-dose therapy using fluorescence in situ hybridization (FISH) analysis. Although the results were difficult to interpret in two patients, 12 of 14 patients had unequivocal persistence of abnormal plasma cells in their bone marrow. Our results suggest that only a few patients, if any, are in true CR following one course of high-dose therapy and are in favor of post-transplantation treatments.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0887-6924
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
641-4
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:10214874-Adult, pubmed-meshheading:10214874-Aged, pubmed-meshheading:10214874-Antineoplastic Agents, Alkylating, pubmed-meshheading:10214874-Bone Marrow, pubmed-meshheading:10214874-Chromosome Aberrations, pubmed-meshheading:10214874-Female, pubmed-meshheading:10214874-Hematopoietic Stem Cell Transplantation, pubmed-meshheading:10214874-Humans, pubmed-meshheading:10214874-In Situ Hybridization, Fluorescence, pubmed-meshheading:10214874-Interphase, pubmed-meshheading:10214874-Male, pubmed-meshheading:10214874-Melphalan, pubmed-meshheading:10214874-Middle Aged, pubmed-meshheading:10214874-Multiple Myeloma, pubmed-meshheading:10214874-Myeloma Proteins, pubmed-meshheading:10214874-Neoplasm, Residual, pubmed-meshheading:10214874-Neoplasm Recurrence, Local, pubmed-meshheading:10214874-Neoplastic Stem Cells, pubmed-meshheading:10214874-Plasma Cells, pubmed-meshheading:10214874-Remission Induction, pubmed-meshheading:10214874-Survival Analysis
pubmed:year
1999
pubmed:articleTitle
Evaluation of minimal residual disease by interphase FISH in multiple myeloma: does complete remission exist?
pubmed:affiliation
Laboratoire d'Hématologie, Angers, France.
pubmed:publicationType
Journal Article