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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1999-6-25
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pubmed:abstractText |
To investigate the degradation of human calcitonin (hCT) by enzymes or mucosa from different gastrointestinal (GI) compartments and evaluate the stabilization effect of a synthetic ionizable copolymer on the stability of hCT in an aqueous solution. These data are a prerequisite for the development of a hydrogel based colon-specific hCT delivery system.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0724-8741
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
359-67
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10213365-Amino Acid Sequence,
pubmed-meshheading:10213365-Animals,
pubmed-meshheading:10213365-Calcitonin,
pubmed-meshheading:10213365-Colon,
pubmed-meshheading:10213365-Humans,
pubmed-meshheading:10213365-Intestinal Mucosa,
pubmed-meshheading:10213365-Intestine, Small,
pubmed-meshheading:10213365-Mass Spectrometry,
pubmed-meshheading:10213365-Microvilli,
pubmed-meshheading:10213365-Molecular Sequence Data,
pubmed-meshheading:10213365-Peptide Hydrolases,
pubmed-meshheading:10213365-Rabbits,
pubmed-meshheading:10213365-Spectrometry, Fluorescence,
pubmed-meshheading:10213365-Spectrophotometry, Ultraviolet
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pubmed:year |
1999
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pubmed:articleTitle |
Degradation and aggregation of human calcitonin in vitro.
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pubmed:affiliation |
Department of Pharmaceutics and Pharmaceutical Chemistry/CCCD, University of Utah, Salt Lake City 84112, USA.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, U.S. Gov't, P.H.S.
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