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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1999-7-6
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|
pubmed:abstractText |
Treatment with lexipafant reduced the severity of pancreatitis-associated endothelial barrier compromise, also associated with a decrease in systemic concentrations of interleukin (IL) 1. Thus, the present findings imply that platelet-activating factor (PAF) may play an important role in the pathogenesis of pancreatic endothelial dysfunction by signaling and triggering the production and release of certain cytokines.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0169-4197
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
45-52
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10211421-Acute Disease,
pubmed-meshheading:10211421-Animals,
pubmed-meshheading:10211421-Body Water,
pubmed-meshheading:10211421-Capillary Permeability,
pubmed-meshheading:10211421-Endothelium, Vascular,
pubmed-meshheading:10211421-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:10211421-Gastrointestinal Hemorrhage,
pubmed-meshheading:10211421-Imidazoles,
pubmed-meshheading:10211421-Interleukin-1,
pubmed-meshheading:10211421-Interleukin-6,
pubmed-meshheading:10211421-Leucine,
pubmed-meshheading:10211421-Male,
pubmed-meshheading:10211421-Microcirculation,
pubmed-meshheading:10211421-Pancreatitis,
pubmed-meshheading:10211421-Platelet Activating Factor,
pubmed-meshheading:10211421-Rats,
pubmed-meshheading:10211421-Rats, Sprague-Dawley,
pubmed-meshheading:10211421-Serum Albumin,
pubmed-meshheading:10211421-Time Factors
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pubmed:year |
1999
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pubmed:articleTitle |
Treatment with lexipafant ameliorates the severity of pancreatic microvascular endothelial barrier dysfunction in rats with acute hemorrhagic pancreatitis.
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pubmed:affiliation |
Department of Surgery, Lund University Hospital, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
