Source:http://linkedlifedata.com/resource/pubmed/id/10211222
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
1999-4-30
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pubmed:abstractText |
Alpha interferon (alpha-IFN) is used for the treatment of various systemic disorders. Side-effects of alpha-IFN therapy can involve numerous organ systems, but sudden hearing loss has only once been recorded. We report a case of sudden hearing loss occurring in a patient with chronic hepatitis C treated with alpha-IFN and recovered five days after the discontinuation of this agent. This is the first record of anti-endothelial cell antibodies detection in a patient with sudden hearing loss. The finding of anti-endothelial cell antibodies suggests an association between sudden hearing loss and microvascular damage during interferon therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-2151
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
112
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
962-3
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10211222-Antiviral Agents,
pubmed-meshheading:10211222-Autoimmune Diseases,
pubmed-meshheading:10211222-Female,
pubmed-meshheading:10211222-Hearing Loss, Sudden,
pubmed-meshheading:10211222-Hepatitis C, Chronic,
pubmed-meshheading:10211222-Humans,
pubmed-meshheading:10211222-Interferon-alpha,
pubmed-meshheading:10211222-Microcirculation,
pubmed-meshheading:10211222-Middle Aged,
pubmed-meshheading:10211222-Tinnitus,
pubmed-meshheading:10211222-Vascular Diseases
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pubmed:year |
1998
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pubmed:articleTitle |
Sudden hearing loss in a patient hepatitis C virus (HCV) positive on therapy with alpha-interferon: a possible autoimmune-microvascular pathogenesis.
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pubmed:affiliation |
Institute of Otolaryngology, Catholic University of the Sacred Heart, Rome, Italy.
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pubmed:publicationType |
Journal Article,
Case Reports
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