Source:http://linkedlifedata.com/resource/pubmed/id/10203849
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1999-6-10
|
| pubmed:abstractText |
Unexpected stimuli that are behaviourally significant have the capacity to elicit a short-latency, short-duration burst of firing in mesencephalic dopaminergic neurones. An influential interpretation of the experimental data that characterize this response proposes that dopaminergic neurones have a crucial role in reinforcement learning because they signal error in the prediction of future reward. In this article we propose a different functional role for this 'short-latency dopamine response' in the mechanisms that underlie associative learning. We suggest that the initial burst of dopaminergic-neurone firing could represent an essential component in the process of switching attentional and behavioural selections to unexpected, behaviourally important stimuli. This switching response could be a crucial prerequisite for associative learning and might be part of a general short-latency response that is mediated by catecholamines and prepares the organism for an appropriate reaction to biologically significant events. Any act which in a given situation produces satisfaction becomes associated with that situation so that when the situation recurs the act is more likely than before to recur also. E.L. Thorndike (1911) 1.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0166-2236
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
22
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
146-51
|
| pubmed:dateRevised |
2009-11-3
|
| pubmed:meshHeading |
pubmed-meshheading:10203849-Action Potentials,
pubmed-meshheading:10203849-Animals,
pubmed-meshheading:10203849-Association,
pubmed-meshheading:10203849-Attention,
pubmed-meshheading:10203849-Avoidance Learning,
pubmed-meshheading:10203849-Basal Ganglia,
pubmed-meshheading:10203849-Behavior, Animal,
pubmed-meshheading:10203849-Catecholamines,
pubmed-meshheading:10203849-Conditioning, Operant,
pubmed-meshheading:10203849-Dopamine,
pubmed-meshheading:10203849-Exploratory Behavior,
pubmed-meshheading:10203849-Humans,
pubmed-meshheading:10203849-Learning,
pubmed-meshheading:10203849-Mesencephalon,
pubmed-meshheading:10203849-Models, Neurological,
pubmed-meshheading:10203849-Models, Psychological,
pubmed-meshheading:10203849-Reaction Time,
pubmed-meshheading:10203849-Reinforcement (Psychology),
pubmed-meshheading:10203849-Reward,
pubmed-meshheading:10203849-Time Factors
|
| pubmed:year |
1999
|
| pubmed:articleTitle |
Is the short-latency dopamine response too short to signal reward error?
|
| pubmed:affiliation |
Dept of Psychology, University of Sheffield, Sheffield, UK S10 2TP.
|
| pubmed:publicationType |
Journal Article,
Review
|