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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1977-4-25
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pubmed:abstractText |
59 patients with far advanced chronic pulmonary tuberculosis were treated, after a three months daily period of RMP/EMB and a third drug, with RMP 1.2 g and EMB 50 mg/kg twice weekly for the following 9 months and there after with EMB 50 mg/kg twice weekly for another 12 months. Sputumconversion was achieved in all patients within four months. Except for one bacteriological relapse during the 10th month of therapy all patients were TB-negative up to the end of at least four years (4-6 1/2 years) after onset of treatment. In nearly 78% of the patients the treatment was fully accepted and well tolerated during the first year. 8 patients had systemic reactions due to RMP between the 7th and 12th month. Only in 5 patients RMP had to be substituted by another drug. The regimen has proved to be highly effective, well acceptable and tolerable. It could be administered fully supervised.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0303-657X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
146
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
145-52
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1020361-Adult,
pubmed-meshheading:1020361-Aged,
pubmed-meshheading:1020361-Drug Therapy, Combination,
pubmed-meshheading:1020361-Ethambutol,
pubmed-meshheading:1020361-Female,
pubmed-meshheading:1020361-Follow-Up Studies,
pubmed-meshheading:1020361-Humans,
pubmed-meshheading:1020361-Male,
pubmed-meshheading:1020361-Methods,
pubmed-meshheading:1020361-Middle Aged,
pubmed-meshheading:1020361-Periodicity,
pubmed-meshheading:1020361-Rifampin,
pubmed-meshheading:1020361-Tuberculosis, Pulmonary
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pubmed:year |
1976
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pubmed:articleTitle |
[Effectivity of intermittent RMP/EMB treatment in patients with chronic pulmonary tuberculosis (author's transl)].
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pubmed:publicationType |
Journal Article,
English Abstract
|