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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4 Suppl
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pubmed:dateCreated |
1999-6-29
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pubmed:abstractText |
Recently, it was recognized that an immune response develops along one of two major pathways. One leads to a destructive immune response (type 1), while the alternative leads to a nondestructive immune response (type 2). Our studies in animal models suggest that therapeutic vaccines induce a tumor-specific type 1 immune response while ineffective vaccines induce a type 2 response. These results have led us to examine the immune response in sentinel lymph nodes draining tumor vaccines of patients entered onto clinical trials for melanoma, breast and renal cell cancer.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0340-6997
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pubmed:author |
pubmed-author:BasheyJJ,
pubmed-author:ChoCC,
pubmed-author:DoranTT,
pubmed-author:FoxB ABA,
pubmed-author:LashleyDD,
pubmed-author:LoweB ABA,
pubmed-author:NgH YHY,
pubmed-author:PuriRR,
pubmed-author:SchusterJJ,
pubmed-author:SmithJ WJW2nd,
pubmed-author:UrbaW JWJ,
pubmed-author:VettoJ TJT,
pubmed-author:WeinbergA DAD,
pubmed-author:WinterHH,
pubmed-author:WoodJJ,
pubmed-author:WoodW JWJ
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S50-3
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10199933-Animals,
pubmed-meshheading:10199933-Breast Neoplasms,
pubmed-meshheading:10199933-Cancer Vaccines,
pubmed-meshheading:10199933-Female,
pubmed-meshheading:10199933-Humans,
pubmed-meshheading:10199933-Kidney Neoplasms,
pubmed-meshheading:10199933-Lymph Nodes,
pubmed-meshheading:10199933-Lymphatic Metastasis,
pubmed-meshheading:10199933-Male,
pubmed-meshheading:10199933-Melanoma,
pubmed-meshheading:10199933-Mice
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pubmed:year |
1999
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pubmed:articleTitle |
Examining the immune response in sentinel lymph nodes of mice and men.
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pubmed:affiliation |
Robert W. Franz Cancer Research Center, Earle A. Chiles Research Institute, Providence Poartland Medical Center, Portland, OR 97213, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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