10198931

Source:http://linkedlifedata.com/resource/pubmed/id/10198931

Download in:

Switch to

Custom View

Named Graph Language Inference

Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0025344, umls-concept:C0032961, umls-concept:C0035647, umls-concept:C0149871, umls-concept:C0449450, umls-concept:C0920317, umls-concept:C1140621, umls-concept:C1561960, umls-concept:C1879329, umls-concept:C1948053, umls-concept:C2347804
pubmed:issue	4
pubmed:dateCreated	1999-5-27
pubmed:abstractText	We performed a meta-analysis of all published studies of deep vein thrombosis during pregnancy and the puerperium using MEDLINE between 1966 and May 1998. Data were pooled using a random effects model. Fourteen studies included relevant information on deep vein thrombosis in pregnancy or the puerperium, and used objective testing to diagnose deep vein thrombosis. The pooled event rate for left sided or bilateral deep vein thrombosis was 82.2 percent (95 percent CI 75.1 to 87.5). There was no statistical evidence of heterogeneity for this figure (P = .08). Twelve studies reported on the trimester in which deep vein thrombosis was diagnosed. The deep vein thrombosis event rate during the first trimester was 21.9 percent (95 percent CI 17.4 to 27.3), 33.7 percent (95 percent CI 28.1 to 39.8) during the second trimester, and 47.6 percent (95 percent CI 39.2 to 56.2) for the third trimester. Heterogeneity testing was not significant. Nine studies compared deep vein thrombosis events between the antepartum and puerperium periods, with 65.5 percent (95 percent CI 58.1 to 72.1) arising during pregnancy, and 34.5 percent (95 percent CI 27.9 to 41.9) postpartum (P = .08, not heterogeneous). Using these figures, the estimated relative distribution of 100 deep vein thrombosis events during pregnancy and the puerperium would be 0.23 per day during pregnancy, and 0.82 per day in the postpartum period. During pregnancy and the puerperium, deep vein thrombosis is more likely to arise in the left leg. More than half of all deep vein thromboses during pregnancy occur during the first and second trimesters. Furthermore, during the puerperium, the risk of developing deep vein thrombosis is significantly higher than antepartum. TARGET AUDIENCE: Obstetricians & Gynecologists, Family Physicians. LEARNING OBJECTIVES: After completion of this article, the reader will be able to understand the incidence and distribution of DVTs during pregnancy and to be able to appreciate the differing risk of DVT during the various time periods in a pregnancy.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0401007
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	0029-7828
pubmed:author	pubmed-author:ChanW SWS, pubmed-author:RayJ GJG
pubmed:issnType	Print
pubmed:volume	54
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	265-71
pubmed:dateRevised	2004-11-17
pubmed:meshHeading	pubmed-meshheading:10198931-Female, pubmed-meshheading:10198931-Humans, pubmed-meshheading:10198931-Incidence, pubmed-meshheading:10198931-Leg, pubmed-meshheading:10198931-Pregnancy, pubmed-meshheading:10198931-Pregnancy Complications, Cardiovascular, pubmed-meshheading:10198931-Puerperal Disorders, pubmed-meshheading:10198931-Risk, pubmed-meshheading:10198931-Venous Thrombosis
pubmed:year	1999
pubmed:articleTitle	Deep vein thrombosis during pregnancy and the puerperium: a meta-analysis of the period of risk and the leg of presentation.
pubmed:affiliation	Department of Medicine, Women's College Hospital, University of Toronto, Canada.
pubmed:publicationType	Journal Article, Meta-Analysis