rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
877
|
pubmed:dateCreated |
1999-4-22
|
pubmed:abstractText |
At our hospital, the number of cases of Clostridium difficile-associated diarrhoea increased from 29 in 1993 to 210 in 1995. The case notes of 110 patients with C difficile-associated diarrhoea during the first 6 months of 1995 were analysed retrospectively. The majority of the patients (106) had received antibiotics before the onset of diarrhoea; 46 had received three or more different antibiotics and 28 had received metronidazole. In 19 patients, the first stool sample after the onset of diarrhoea was negative for C difficile cytotoxin, with a mean delay of 8.2 days before a positive stool sample. We conclude that C difficile-associated diarrhoea was associated with the usage of multiple antibiotics, and that metronidazole did not protect against colonisation by C difficile. We also recommend that more than one stool sample should be tested for the C difficile cytotoxin.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0032-5473
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
74
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
677-8
|
pubmed:dateRevised |
2009-11-18
|
pubmed:meshHeading |
pubmed-meshheading:10197216-Adult,
pubmed-meshheading:10197216-Aged,
pubmed-meshheading:10197216-Aged, 80 and over,
pubmed-meshheading:10197216-Anti-Bacterial Agents,
pubmed-meshheading:10197216-Cross Infection,
pubmed-meshheading:10197216-Diarrhea,
pubmed-meshheading:10197216-Enterocolitis, Pseudomembranous,
pubmed-meshheading:10197216-Female,
pubmed-meshheading:10197216-Humans,
pubmed-meshheading:10197216-Male,
pubmed-meshheading:10197216-Middle Aged,
pubmed-meshheading:10197216-Retrospective Studies
|
pubmed:year |
1998
|
pubmed:articleTitle |
Clostridium difficile-associated diarrhoea.
|
pubmed:affiliation |
Division of Gastroenterology, University Hospital, Queen's Medical Centre, Nottingham, UK.
|
pubmed:publicationType |
Journal Article
|