Source:http://linkedlifedata.com/resource/pubmed/id/10195247
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1999-5-6
|
| pubmed:abstractText |
We wished to generate a number of genetic constructs containing mutations in the protease (PR) and reverse transcriptase (RT) genes of the Gag-Pol of human immunodeficiency virus type 1 (HIV-1) and to transfect these constructs into COS-7 cells to determine their effect on wild-type (wt) viral replication.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
1090-9508
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
240-7
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:10195247-Animals,
pubmed-meshheading:10195247-Binding Sites,
pubmed-meshheading:10195247-COS Cells,
pubmed-meshheading:10195247-Cloning, Molecular,
pubmed-meshheading:10195247-Fusion Proteins, gag-pol,
pubmed-meshheading:10195247-HIV-1,
pubmed-meshheading:10195247-Humans,
pubmed-meshheading:10195247-Mutation,
pubmed-meshheading:10195247-Plasmids,
pubmed-meshheading:10195247-Transfection,
pubmed-meshheading:10195247-Virus Replication
|
| pubmed:articleTitle |
Cotransfection of mutated forms of human immunodeficiency virus type 1 Gag-Pol with wild-type constructs can interfere with processing and viral replication.
|
| pubmed:affiliation |
McGill University AIDS Centre, Lady Davis Institute-Jewish General Hospital, Montreal, Quebec, Canada.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|