Source:http://linkedlifedata.com/resource/pubmed/id/10195146
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1999-4-20
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pubmed:abstractText |
Pain and temperature stimuli activate neurons of lamina I within the dorsal horn of the spinal cord, and although these neurons can be classified into three basic morphological types and three major physiological classes, earlier studies did not establish a structure/function correlation between their morphology and their physiological responses. We recorded and intracellularly labeled 38 cat lamina I neurons. All 12 fusiform cells were nociceptive-specific, responsive only to pinch and/or heat. All 11 pyramidal cells were thermoreceptive-specific, responsive only to innocuous cooling. Of ten multipolar cells, six were polymodal, responsive to heat, pinch and cold, and four were nociceptive-specific. Five unclassified cells had features consistent with this pattern. These results support the view that central pain and temperature pathways contain anatomically discrete sets of modality-selective neurons.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1097-6256
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
218-25
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10195146-Animals,
pubmed-meshheading:10195146-Cats,
pubmed-meshheading:10195146-Cold Temperature,
pubmed-meshheading:10195146-Electrophysiology,
pubmed-meshheading:10195146-Female,
pubmed-meshheading:10195146-Hot Temperature,
pubmed-meshheading:10195146-Male,
pubmed-meshheading:10195146-Neurons,
pubmed-meshheading:10195146-Nociceptors,
pubmed-meshheading:10195146-Pain,
pubmed-meshheading:10195146-Physical Stimulation,
pubmed-meshheading:10195146-Pyramidal Cells,
pubmed-meshheading:10195146-Spinal Cord,
pubmed-meshheading:10195146-Thermoreceptors
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pubmed:year |
1998
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pubmed:articleTitle |
Nociceptive and thermoreceptive lamina I neurons are anatomically distinct.
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pubmed:affiliation |
Division of Neurobiology, Barrow Neurological Institute, Phoenix, Arizona 85013, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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