Source:http://linkedlifedata.com/resource/pubmed/id/10193910
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1999-6-24
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pubmed:abstractText |
Cyclosporine, a calcineurin inhibitor, significantly enhances spontaneous acetylcholine release after a brief tetanus and potentiates the effect of phorbol 12,13-dibutyrate. Both actions are prevented by the protein kinase C inhibitor, bisindolylmaleimide iodide. Protein kinase C and calcineurin thus play important roles in the balance between phosphorylation and dephosphorylation regulating spontaneous transmitter release at motor nerve terminals.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0028-3908
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
195-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10193910-Acetylcholine,
pubmed-meshheading:10193910-Analysis of Variance,
pubmed-meshheading:10193910-Animals,
pubmed-meshheading:10193910-Calcineurin,
pubmed-meshheading:10193910-Cyclosporine,
pubmed-meshheading:10193910-Enzyme Inhibitors,
pubmed-meshheading:10193910-Mice,
pubmed-meshheading:10193910-Mice, Inbred ICR,
pubmed-meshheading:10193910-Motor Neurons,
pubmed-meshheading:10193910-Nerve Endings,
pubmed-meshheading:10193910-Phosphorylation,
pubmed-meshheading:10193910-Tetany
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pubmed:year |
1999
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pubmed:articleTitle |
Enhanced spontaneous transmitter release at murine motor nerve terminals with cyclosporine.
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pubmed:affiliation |
Institute of Pharmacology, National Taiwan University, College of Medicine, Taipei, ROC.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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