| pubmed-article:10191767 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10191767 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:10191767 | lifeskim:mentions | umls-concept:C0005768 | lld:lifeskim |
| pubmed-article:10191767 | lifeskim:mentions | umls-concept:C0005953 | lld:lifeskim |
| pubmed-article:10191767 | lifeskim:mentions | umls-concept:C0024314 | lld:lifeskim |
| pubmed-article:10191767 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:10191767 | lifeskim:mentions | umls-concept:C0449450 | lld:lifeskim |
| pubmed-article:10191767 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:10191767 | pubmed:dateCreated | 1999-4-16 | lld:pubmed |
| pubmed-article:10191767 | pubmed:abstractText | We studied 40 patients with CD5- B-cell lymphoproliferative disorders (B-LPDs) presenting in blood or bone marrow and 28 control patients with CD5+ B-cell chronic lymphocytic leukemia (CLL). Fifteen study patients had morphologic features typical of CLL. The 15 patients with CD5- CLL were older and had lower absolute lymphocyte counts and more advanced-stage disease at diagnosis than controls. Ten study patients had morphologic features suggesting mantle cell lymphoma (MCL); 3 were later given a diagnosis of MCL based on lymph node biopsy results. The 10 patients with CD5- MCL were older and at a more advanced stage than CLL control patients. The remaining 15 study patients were given the following diagnoses: circulating non-Hodgkin lymphoma, 5; splenic lymphoma with villous lymphocytes, 5; lymphoplasmacytoid lymphoma, 3; and CLL/pro-lymphocytic leukemia, 2. For the patients with CD5- B-LPDs with morphologic features and manifestations resembling CLL, we prefer the term CD5- CLL variant because of clinical and immunophenotypic differences. Patients with CD5- B-LPDs with atypical nuclear morphologic features may represent the leukemic phase of MCL. Since CD23 is expressed in most patients with CD5- B-LPD, its use in subclassifying these disorders seems limited. | lld:pubmed |
| pubmed-article:10191767 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10191767 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10191767 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:10191767 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10191767 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10191767 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10191767 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:10191767 | pubmed:issn | 0002-9173 | lld:pubmed |
| pubmed-article:10191767 | pubmed:author | pubmed-author:MillerM LML | lld:pubmed |
| pubmed-article:10191767 | pubmed:author | pubmed-author:ShapiroJ LJL | lld:pubmed |
| pubmed-article:10191767 | pubmed:author | pubmed-author:FishlederA... | lld:pubmed |
| pubmed-article:10191767 | pubmed:author | pubmed-author:MaschaEE | lld:pubmed |
| pubmed-article:10191767 | pubmed:author | pubmed-author:PohlmanBB | lld:pubmed |
| pubmed-article:10191767 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10191767 | pubmed:volume | 111 | lld:pubmed |
| pubmed-article:10191767 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10191767 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10191767 | pubmed:pagination | 477-87 | lld:pubmed |
| pubmed-article:10191767 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:10191767 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10191767 | pubmed:articleTitle | CD5- B-cell lymphoproliferative disorders presenting in blood and bone marrow. A clinicopathologic study of 40 patients. | lld:pubmed |
| pubmed-article:10191767 | pubmed:affiliation | Department of Pathology, Cleveland Clinic Foundation, Ohio 44195, USA. | lld:pubmed |
| pubmed-article:10191767 | pubmed:publicationType | Journal Article | lld:pubmed |
