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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1977-4-15
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pubmed:abstractText |
B6/c mice do not develop spontaneous positive direct Coomb's tests (DCT), but they are highly susceptible to the induction of erythrocyte auto-antibodies by immunization with cross reacting rat blood cells (36% positive DCT). Rauscher leukemogenic virus (RLV) does not directly induce DCT in these susceptible mice; neither does the inoculation of parental spleen cells. On the other hand both RLV and allogeneic stimulation by parental spleen cells enhance the incidence of the rat blood cell-induced DCT (up to 75% and 69% respectively). This is discussed in terms of a separate etiology to antinuclear and anti-erythrocyte auto-antibodies and of the possible mechanisms of auto-immune stimulation by oncogenic viruses or allogeneic stimulation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0300-0893
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
395-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1016681-Animals,
pubmed-meshheading:1016681-Antibody Formation,
pubmed-meshheading:1016681-Autoantibodies,
pubmed-meshheading:1016681-Coombs' Test,
pubmed-meshheading:1016681-Erythrocytes,
pubmed-meshheading:1016681-Female,
pubmed-meshheading:1016681-Male,
pubmed-meshheading:1016681-Mice,
pubmed-meshheading:1016681-Rats,
pubmed-meshheading:1016681-Rauscher Virus,
pubmed-meshheading:1016681-Spleen,
pubmed-meshheading:1016681-Transplantation, Homologous
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pubmed:year |
1976
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pubmed:articleTitle |
Enhancement of murine erythrocyte auto-antibody responses by Rauscher leukemogenic virus and by a weak allogeneic stimulation.
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pubmed:publicationType |
Journal Article
|